ZM12875A1 - Purine compounds and salts thereof - Google Patents

Purine compounds and salts thereof

Info

Publication number
ZM12875A1
ZM12875A1 ZM128/75A ZM12875A ZM12875A1 ZM 12875 A1 ZM12875 A1 ZM 12875A1 ZM 128/75 A ZM128/75 A ZM 128/75A ZM 12875 A ZM12875 A ZM 12875A ZM 12875 A1 ZM12875 A1 ZM 12875A1
Authority
ZM
Zambia
Prior art keywords
salts
purine compounds
purine
compounds
Prior art date
Application number
ZM128/75A
Other languages
English (en)
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10402412&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZM12875(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of ZM12875A1 publication Critical patent/ZM12875A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Saccharide Compounds (AREA)
ZM128/75A 1974-09-02 1975-09-02 Purine compounds and salts thereof ZM12875A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB38278/74A GB1523865A (en) 1974-09-02 1974-09-02 Purine compunds and salts thereof

Publications (1)

Publication Number Publication Date
ZM12875A1 true ZM12875A1 (en) 1977-09-21

Family

ID=10402412

Family Applications (1)

Application Number Title Priority Date Filing Date
ZM128/75A ZM12875A1 (en) 1974-09-02 1975-09-02 Purine compounds and salts thereof

Country Status (35)

Country Link
US (3) US4294831A (en])
JP (1) JPS5154589A (en])
AR (4) AR220299A1 (en])
AT (1) AT354462B (en])
AU (1) AU503160B2 (en])
BE (1) BE833006A (en])
BG (4) BG26536A4 (en])
CA (1) CA1062257A (en])
CH (7) CH626363A5 (en])
CS (2) CS203092B2 (en])
CY (1) CY1033A (en])
DD (1) DD122092A5 (en])
DE (1) DE2539963C2 (en])
DK (1) DK146595C (en])
ES (3) ES440631A1 (en])
FI (1) FI60709C (en])
FR (1) FR2282892A1 (en])
GB (1) GB1523865A (en])
HK (1) HK84379A (en])
HU (1) HU176730B (en])
IE (1) IE42282B1 (en])
IL (1) IL48035A (en])
KE (1) KE3002A (en])
LU (1) LU73304A1 (en])
MC (1) MC1068A1 (en])
MY (1) MY8200191A (en])
NL (1) NL175061C (en])
NO (1) NO144216C (en])
NZ (1) NZ178556A (en])
RO (4) RO74274A (en])
SE (1) SE428562C (en])
SU (7) SU904523A3 (en])
YU (4) YU39947B (en])
ZA (1) ZA755574B (en])
ZM (1) ZM12875A1 (en])

Families Citing this family (120)

* Cited by examiner, † Cited by third party
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AU521577B2 (en) * 1977-02-24 1982-04-22 Wellcome Foundation Limited, The 9-hydroxyethoxymethyl guanine phosphates
US4287188A (en) 1977-02-24 1981-09-01 Burroughs Wellcome Co. Purine derivatives
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US4347360A (en) * 1980-09-16 1982-08-31 Ens Bio Logicals Inc. Ring open nucleoside analogues
US5157120A (en) * 1980-09-16 1992-10-20 Syntex (U.S.A.) Inc. Guanine derivatives
AU547311B2 (en) * 1980-10-15 1985-10-17 Wellcome Foundation Limited, The Treating viral infections in fish
US4355032B2 (en) * 1981-05-21 1990-10-30 9-(1,3-dihydroxy-2-propoxymethyl)guanine as antiviral agent
US4603219A (en) * 1981-05-21 1986-07-29 Syntex (U.S.A.) Inc. 1,3-dibenzyloxy-2-acetoxymethoxypropane, intermediate for 9-(1,3-dihydroxy-2-propoxymethyl)guanine
US4423050A (en) * 1981-05-21 1983-12-27 Syntex (U.S.A.) Inc. 9-(1,3-Dihydroxy-2-propoxymethyl)guanine as antiviral agent
NZ201547A (en) * 1981-08-11 1986-01-24 Wellcome Found Purine derivatives and antiviral compositions
ES8403906A1 (es) * 1981-09-16 1984-04-01 Ens Bio Logicals Inc "procedimiento para preparar derivados de 9-(etoximetil)-guanina".
AU564576B2 (en) * 1981-09-24 1987-08-20 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Purine derivatives
US5250535A (en) * 1982-02-01 1993-10-05 Syntex Inc. Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl) purines as antiviral agent
ATE24836T1 (de) * 1982-02-12 1987-01-15 Ens Bio Logicals Inc Antivirale zusammensetzungen.
SE8203855D0 (sv) * 1982-06-21 1982-06-21 Astra Laekemedel Ab Novel derivatives of guanine i
SE8203856D0 (sv) * 1982-06-21 1982-06-21 Astra Laekemedel Ab Novel derivatives of guanine ii
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US4609662A (en) * 1982-10-14 1986-09-02 Burroughs Wellcome Co. Method for using purine derivatives
US4745119A (en) * 1982-10-14 1988-05-17 Burroughs Wellcome Co. Method for using purine derivatives
US5059604A (en) * 1982-10-14 1991-10-22 Burroughs Wellcome Co. 2-amino purine derivatives
US4649140A (en) * 1982-10-14 1987-03-10 Burroughs Wellcome Co. Purine derivatives
KR890001487B1 (ko) * 1982-10-14 1989-05-04 더 웰컴 파운데이숀 리미티드 푸린 유도체의 제조방법
US4612314A (en) * 1982-12-22 1986-09-16 Syntex (U.S.A.) Inc. Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl) purines as antiviral agent
US4461757A (en) * 1983-02-23 1984-07-24 Ens Bio Logicals Inc. Dimethylaminomethylenated anti-herpes compounds
ES520140A0 (es) * 1983-02-25 1984-04-01 Ind Farma Especial Un procedimiento para la preparacion de acicloguanosina.
US5047533A (en) * 1983-05-24 1991-09-10 Sri International Acyclic purine phosphonate nucleotide analogs
US4557934A (en) 1983-06-21 1985-12-10 The Procter & Gamble Company Penetrating topical pharmaceutical compositions containing 1-dodecyl-azacycloheptan-2-one
US4880820A (en) * 1983-06-24 1989-11-14 Merck & Co., Inc. Guanine derivatives
JPS6023380A (ja) * 1983-06-24 1985-02-05 メルク・エンド・カムパニー・インコーポレーテッド 抗ウイルス剤
US5684153A (en) * 1984-08-16 1997-11-04 Beecham Group Plc Process for the preparation of purine derivatives
US4897479A (en) * 1983-09-30 1990-01-30 Merck & Co., Inc. Arylsulfonyloxy purine intermediates
JPS6094992A (ja) * 1983-10-28 1985-05-28 Sankyo Co Ltd グリゼオ−ル酸誘導体
IE842642L (en) * 1983-10-31 1985-04-30 Harvard College Purine Derivatives
US4806642A (en) * 1984-10-05 1989-02-21 Warner-Lambert Company Purine derivatives
ZA848080B (en) * 1983-10-31 1985-06-26 Warner Lambert Co Purine derivatives
US4918219A (en) * 1983-10-31 1990-04-17 Warner-Lambert Company Glycerine derivatives
US4579849A (en) * 1984-04-06 1986-04-01 Merck & Co., Inc. N-alkylguanine acyclonucleosides as antiviral agents
US4617304A (en) * 1984-04-10 1986-10-14 Merck & Co., Inc. Purine derivatives
IL74881A0 (en) * 1984-04-13 1985-07-31 Wellcome Found Purine derivatives,their preparation and pharmaceutical compositions containing them
US4636507A (en) * 1984-04-30 1987-01-13 Hoechst-Roussel Pharmaceuticals Inc. Host defense mechanism enhancement
JPH0625061B2 (ja) 1984-07-03 1994-04-06 ザ ウエルカム フアウンデ−シヨン リミテツド 抗ウイルス性化合物
WO1986000901A1 (en) * 1984-07-20 1986-02-13 Gauntt Charles O Immunoregulatory and anti-viral compound
SE8406538D0 (sv) * 1984-12-21 1984-12-21 Astra Laekemedel Ab Novel derivatives of purine
US4724232A (en) * 1985-03-16 1988-02-09 Burroughs Wellcome Co. Treatment of human viral infections
US5683990A (en) * 1985-03-16 1997-11-04 Glaxo Wellcome Inc. Treatment of human viral infections
CS263952B1 (en) * 1985-04-25 1989-05-12 Holy Antonin Remedy with antiviral effect
CS263951B1 (en) * 1985-04-25 1989-05-12 Antonin Holy 9-(phosponylmethoxyalkyl)adenines and method of their preparation
IL78643A0 (en) * 1985-05-02 1986-08-31 Wellcome Found Purine derivatives,their preparation and pharmaceutical compositions containing them
DE3667058D1 (en) 1985-05-02 1989-12-28 Wellcome Found Antiviral compounds
DE3529497A1 (de) * 1985-08-17 1987-02-26 Boehringer Mannheim Gmbh N(pfeil hoch)6(pfeil hoch)-disubstituierte purinderivate, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
DE3627024A1 (de) * 1985-09-24 1987-04-02 Hoechst Ag In 6- und 9-stellung substituierte 2-aminopurine, ihre verwendung, diese purine enthaltende arzneimittel und verfahren zur herstellung der purine
IT1207507B (it) * 1985-10-21 1989-05-25 Baldacci Lab Spa Coniugato della 9-(2-idrossietossimetil)guanina con albumina umana lattosaminata, procedimento per la sua preparazione e composizioni farmaceutiche che la contengono.
DE3782427T2 (de) * 1986-10-06 1996-07-18 Univ Virginia Verwendung einer adenosin, hypoxanthin und ribose enthaltender lösung zur schonung des herzens während chirurgischer eingriffe.
JPH01501478A (ja) * 1986-11-25 1989-05-25 インスティテュト　オルガニチェスコゴ　シンテザ　アカデミイ　ナウク　ラトビイスコイ　エスエスアール ９―置換グアニン
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US4829055A (en) * 1987-01-23 1989-05-09 Naficy Sadeque S Method of treatment for herpes infections of external tissues
US5565566A (en) * 1987-04-24 1996-10-15 Discovery Therapeutics, Inc. N6 -substituted 9-methyladenines: a new class of adenosine receptor antagonists
US6306647B1 (en) 1987-06-16 2001-10-23 Ajinomoto Co., Inc. Process for producing and purifying 2′,3′-dideoxynucleosides, and process for producing 2′,3′-dideoxy-2′,3′-didehydronucleosides
US4835104A (en) * 1987-06-16 1989-05-30 Ajinomoto Co., Inc., Patent & Licensing Department Process for producing and purifying 2',3'-dideoxynucleosides, and process for producing 2',3'-dideoxy-2',3'-didehydronucleosides
GB8719367D0 (en) * 1987-08-15 1987-09-23 Wellcome Found Therapeutic compounds
GB8725939D0 (en) * 1987-11-05 1987-12-09 Wellcome Found Therapeutic compounds
CA1302887C (en) * 1987-11-24 1992-06-09 Yves Langelier Combination of acyclovir or a derivative thereof and bacitracin
JPH01121424U (en]) * 1988-02-10 1989-08-17
GB8815241D0 (en) * 1988-06-27 1988-08-03 Wellcome Found Antiviral combinations & compounds therefor
US5164395A (en) * 1988-06-27 1992-11-17 Burroughs Wellcome Co. Antiviral acetyl pyridine derivative or said acetyl pyridine derivative in combination with acyclovir
GB8816760D0 (en) * 1988-07-14 1988-08-17 Wellcome Found Therapeutic compounds
JPH02164881A (ja) * 1988-10-24 1990-06-25 Wellcome Found Ltd:The 治療用ヌクレオシド化合物
KR910700253A (ko) * 1989-01-31 1991-03-14 로버트 제이, 바란 N_6-치환-9-메틸아데닌: 신규한 부류의 아데노신 수용체 길항질
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Family Cites Families (2)

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Publication number Priority date Publication date Assignee Title
US4199574A (en) * 1974-09-02 1980-04-22 Burroughs Wellcome Co. Methods and compositions for treating viral infections and guanine acyclic nucleosides
US4146715A (en) * 1975-08-27 1979-03-27 Burroughs Wellcome Co. 2-amido-9-(2-acyloxyethoxymethyl)hypoxanthines

Also Published As

Publication number Publication date
FI752465A7 (en]) 1976-03-03
SE428562C (sv) 1985-11-18
NO144216B (no) 1981-04-06
BE833006A (fr) 1976-03-02
IE42282B1 (en) 1980-07-16
SU751325A3 (ru) 1980-07-23
AU503160B2 (en) 1979-08-23
CH626363A5 (en]) 1981-11-13
FI60709B (fi) 1981-11-30
SE7509675L (sv) 1976-03-03
CS203092B2 (en) 1981-02-27
BG24815A3 (bg) 1978-05-12
US4360522A (en) 1982-11-23
FR2282892A1 (fr) 1976-03-26
HU176730B (en) 1981-04-28
DK146595C (da) 1984-04-24
SU686618A3 (ru) 1979-09-15
FR2282892B1 (en]) 1980-04-25
YU119982A (en) 1982-08-31
RO74275A (ro) 1981-09-24
AT354462B (de) 1979-01-10
FI60709C (fi) 1982-03-10
YU120182A (en) 1982-08-31
CY1033A (en) 1980-08-01
RO74276A (ro) 1981-06-26
ZA755574B (en) 1977-04-27
ES440631A1 (es) 1977-06-16
DK392675A (da) 1976-03-03
DE2539963C2 (de) 1987-01-22
CH629206A5 (de) 1982-04-15
NO753009L (en]) 1976-03-03
ES455978A1 (es) 1978-01-16
YU39947B (en) 1985-06-30
MC1068A1 (fr) 1976-05-21
SU700064A3 (ru) 1979-11-25
CH628897A5 (de) 1982-03-31
YU40080B (en) 1985-06-30
IE42282L (en) 1976-03-02
AU8445975A (en) 1977-03-10
IL48035A (en) 1981-07-31
RO74274A (ro) 1981-09-24
DK146595B (da) 1983-11-14
HK84379A (en) 1979-12-14
IL48035A0 (en) 1975-11-25
JPS6147839B2 (en]) 1986-10-21
ES455979A1 (es) 1978-01-16
BG26389A3 (bg) 1979-03-15
CH626364A5 (en]) 1981-11-13
YU40079B (en) 1985-06-30
CH623586A5 (en]) 1981-06-15
YU222075A (en) 1982-08-31
AR220885A1 (es) 1980-12-15
BG26536A4 (bg) 1979-04-12
CS203093B2 (en) 1981-02-27
MY8200191A (en) 1982-12-31
YU120082A (en) 1982-08-31
SU904523A3 (ru) 1982-02-07
NL175061B (nl) 1984-04-16
BG25094A3 (bg) 1978-07-12
CH629805A5 (de) 1982-05-14
GB1523865A (en) 1978-09-06
AR220508A1 (es) 1980-11-14
US4294831A (en) 1981-10-13
US4323573A (en) 1982-04-06
DE2539963A1 (de) 1976-03-18
NL175061C (nl) 1984-09-17
AR212914A1 (es) 1978-11-15
NL7510342A (nl) 1976-03-04
KE3002A (en) 1979-12-14
SE428562B (sv) 1983-07-11
CA1062257A (en) 1979-09-11
SU858569A3 (ru) 1981-08-23
RO76939A (ro) 1981-06-22
SU784777A3 (ru) 1980-11-30
DD122092A5 (en]) 1976-09-12
SU799664A3 (ru) 1981-01-23
NO144216C (no) 1981-07-15
CH623587A5 (en]) 1981-06-15
NZ178556A (en) 1978-09-25
ATA676375A (de) 1979-06-15
AR220299A1 (es) 1980-10-31
JPS5154589A (en) 1976-05-13
LU73304A1 (en]) 1976-08-13

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